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Fig. 5 | Microbial Cell Factories

Fig. 5

From: TAK-242 ameliorates DSS-induced colitis by regulating the gut microbiota and the JAK2/STAT3 signaling pathway

Fig. 5

Effects of TAK-242 on the expression of p-JAK2/p-STAT3 in colitis tissue. The protein expression levels of p-JAK2 and p-STAT3 were evaluated by western blotting. β-Actin was used as an internal control. a The relative band intensity was measured compared with β-actin. b The relative band intensity was measured compared with JAK2 and STAT3. Compared with the control group, the DSS group showed an obvious downregulation of the protein expression of p-JAK2 and p-STAT3 levels (**p < 0.01, ***p < 0.001). Compared with the DSS group, TAK242 significantly enhanced the expression of p-JAK2 and p-STAT3 (#p < 0.05, ##p < 0.01, ###p < 0.001)

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