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Table 1 CCD and ANN design matrix of variables with experimental and predicted response for xylitol production

From: Biovalorisation of crude glycerol and xylose into xylitol by oleaginous yeast Yarrowia lipolytica

Experiment no.

Xylose (g/L)

NH4Cl (w/v  %)

YNB (w/v  %)

Phosphate buffer (mM)

Xylitol (g/L)

CCD predicted

ANN predicted

1

20

0.2

0.2

35

17.47

18.04

18.79

2

50

0.2

0.2

35

22.20

22.80

22.48

3

20

0.5

0.2

35

13.11

11.81

14.99

4

50

0.5

0.2

35

20.05

19.51

20.45

5

20

0.2

0.5

35

10.20

10.52

4.83

6

50

0.2

0.5

35

21.77

22.48

19.70

7

20

0.5

0.5

35

18.70

20.81

18.92

8

50

0.5

0.5

35

37.22

35.73

33.50

9

20

0.2

0.2

100

18.99

26.02

23.06

10

50

0.2

0.2

100

29.53

27.94

30.42

11

20

0.5

0.2

100

17.85

17.65

19.66

12

50

0.5

0.2

100

23.30

22.52

23.14

13

20

0.2

0.5

100

4.74

5.79

5.90

14

50

0.2

0.5

100

14.07

14.91

13.92

15

20

0.5

0.5

100

15.00

13.95

14.27

16

50

0.5

0.5

100

26.08

26.03

31.47

17

35

0.35

0.35

67.5

20.71

24.25

24.96

18

35

0.35

0.35

67.5

27.18

24.25

24.96

19

35

0.35

0.35

67.5

24.53

24.25

24.96

20

35

0.35

0.35

67.5

24.84

24.25

24.96

21

5

0.35

0.35

67.5

20.57

19.33

21.37

22

65

0.35

0.35

67.5

34.98

36.16

37.22

23

35

0.05

0.35

67.5

12.41

10.67

11.56

24

35

0.65

0.35

67.5

13.88

15.55

15.66

25

35

0.35

0.05

67.5

29.69

30.82

29.96

26

35

0.35

0.65

67.5

28.00

26.80

23.25

27

35

0.35

0.35

2.5

23.62

23.15

23.75

28

35

0.35

0.35

132.5

21.03

21.43

21.08

29

35

0.35

0.35

67.5

24.87

27.46

24.96

30

35

0.35

0.35

67.5

29.78

27.46

24.96