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Fig. 5 | Microbial Cell Factories

Fig. 5

From: Heterologous reconstitution of the biosynthesis pathway for 4-demethyl-premithramycinone, the aglycon of antitumor polyketide mithramycin

Fig. 5

UHPLC analysis at 280 nm of organic extracts of S. albus strains expressing different cassette plasmids. aS. albus pEM4 (control); bS. albus pDZPKS1; cS. albus pDZPKSQ; dS. albus pDZPKS9; eS. albus pDZPKS8; fS. albus pDZPKS5; gS. albus pDZPKS5 + 15; hS. albus pDZPKS5 + 21. Chromatograms are shown at the same scale. 1, SEK15; 2, 2-hydroxy nogalonic acid; 3-5, unknown compounds; 6, 4-demethyl-premithramycinone

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