Fig. 5From: Heterologous reconstitution of the biosynthesis pathway for 4-demethyl-premithramycinone, the aglycon of antitumor polyketide mithramycinUHPLC analysis at 280 nm of organic extracts of S. albus strains expressing different cassette plasmids. aS. albus pEM4 (control); bS. albus pDZPKS1; cS. albus pDZPKSQ; dS. albus pDZPKS9; eS. albus pDZPKS8; fS. albus pDZPKS5; gS. albus pDZPKS5 + 15; hS. albus pDZPKS5 + 21. Chromatograms are shown at the same scale. 1, SEK15; 2, 2-hydroxy nogalonic acid; 3-5, unknown compounds; 6, 4-demethyl-premithramycinoneBack to article page