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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Heterologous reconstitution of the biosynthesis pathway for 4-demethyl-premithramycinone, the aglycon of antitumor polyketide mithramycin

Fig. 1

Expression of cosAR7 in S. albus. a Genetic organization of cluster mtm from Streptomyces argillaceus. b UHPLC analysis at 280 nm of organic extracts of S. albus pKC505 (control). c UHPLC analysis at 280 nm of organic extracts of S. albus cosAR7-R. Black line indicates mtm genes contained in cosmid cosAR7. Chromatograms are shown at the same scale. 4DMPC, 4-demethyl-premithramycinone

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Microbial Cell Factories

ISSN: 1475-2859

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