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Fig. 2 | Microbial Cell Factories

Fig. 2

From: Homology-dependent recombination of large synthetic pathways into E. coli genome via λ-Red and CRISPR/Cas9 dependent selection methodology

Fig. 2

a MEP pathway and related metabolism showing the major metabolic regulatory points. d-glyceraldehyde 3-phosphate (G-3P);1-deoxy-d-xylulose 5-phosphate (DXP); methylerythritol 4-phosphate (MEP); diphosphocytidyl methylerythritol (CDP-ME); diphosphocytidyl methylerythritol 2-phosphate (CDP-MEP); hydroxymethylbutenyl diphosphate (HMBPP); isopentenyl diphosphate (IPP); dimethylallyl diphosphate (DMAPP); farnesyl diphosphate (FPP). b The limiting step for lycopene production was divided into three modules. The feedforward module including dxs and dxr, feedback module including idi and crtE and lycopene synthetic module including crtI, crtE and crtB for lycopene production

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Microbial Cell Factories

ISSN: 1475-2859

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