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Fig. 4 | Microbial Cell Factories

Fig. 4

From: In vitro and in vivo recombination of heterologous modules for improving biosynthesis of astaxanthin in yeast

Fig. 4

The comparison between the in vitro and the in vivo evolution of heterologous modular pathway of astaxanthin. a Phenotype verification of yQDD008 and yQDD022. The parent strain yQDD001 was used as control strain. The photograph was attached to illustrate the visual color of the related strains. b Stability assays of yQDD008 and yQDD022. Yeast cultures in YPD after 6 days were plated on SD agar and the number of light-color strains was counted. The ratio of unstable strains in every 12 generations was recorded and listed. c Growth curves of yQDD001, yQDD008 and yQDD022. d Profile of astaxanthin titer during fermentation with strain yQDD001, yQDD008 and yQDD022. e Profile of astaxanthin yield during fermentation with strain yQDD001, yQDD008 and yQDD022

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