Fig. 4From: In vitro and in vivo recombination of heterologous modules for improving biosynthesis of astaxanthin in yeastThe comparison between the in vitro and the in vivo evolution of heterologous modular pathway of astaxanthin. a Phenotype verification of yQDD008 and yQDD022. The parent strain yQDD001 was used as control strain. The photograph was attached to illustrate the visual color of the related strains. b Stability assays of yQDD008 and yQDD022. Yeast cultures in YPD after 6 days were plated on SD agar and the number of light-color strains was counted. The ratio of unstable strains in every 12 generations was recorded and listed. c Growth curves of yQDD001, yQDD008 and yQDD022. d Profile of astaxanthin titer during fermentation with strain yQDD001, yQDD008 and yQDD022. e Profile of astaxanthin yield during fermentation with strain yQDD001, yQDD008 and yQDD022Back to article page