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Table 3 PHA production by haloarchaea using various substrates

From: Current developments on polyhydroxyalkanoates synthesis by using halophiles as a promising cell factory

Microorganism

Carbon source

PHA type

PHA production

Fermentation operation mode

References

Har. hispanica

Glucose

P(3HB-co-3.18 mol% 3HV)

Content of 12.26% (wt)

Shake flasks

[105]

Har. marismortui

100% pre-treated vinasse

PHB

Content of 30% (wt); yield of 0.77 g/g; productivity of 0.02 g/L/h

Shake flasks

[69]

Hfx. mediterranei

Glucose

P(3HB-co-12.4 mol% 3HV)

Content of 16.4% (wt)

Shake flasks

[35]

Hfx. mediterranei

Extruded starch

P(3HB-co-10.4 mol% 3HV)

Content of 50.8% (wt)

Fed-batch

[85]

Hfx. mediterranei

25% pre-treated vinasse

P(3HB-co-12.36 mol% 3HV)

Content of 70% (wt); yield of 0.87 g/g; productivity of 0.21 g/L/h

Shake flasks

[61]

Hfx. mediterranei

50% pre-treated vinasse

P(3HB-co-14.09 mol% 3HV)

Content of 66% (wt); yield of 0.52 g/g; productivity of 0.18 g/L/h

Shake flasks

[61]

Hfx. mediterranei

Olive mill wastewater

P(3HB-co-6.5 mol% 3HV)

Content of 43% (wt)

Shake flasks

[62]

Hfx. mediterranei

Enzymatic hydrolysate of cheese whey

P(3HB-co-6 mol% 3HV)

Content of 72.8% (wt), yield of 0.29 g/g; productivity of 0.09 g/L/h

42-L bioreactor

[23]

Hfx. mediterranei

Chemical hydrolysate of cheese whey

P(3HB-co-1.5 mol% 3HV)

Content of 53% (wt); yield of 0.78 g/g; productivity of 4.04 g/L/day

2-L bioreactor

[64]

Hfx. mediterranei

Waste stillage

P(3HB-co-15.4 mol% 3HV)

Content of 71% (wt); yield of 0.35 g/g; productivity of 0.17 g/L/h

Shake flasks

[65]

Hfx. mediterranei

Waste stillage

P(3HB-co-17.9 mol% 3HV)

Content of 63% (wt); yield of 0.27 g/g; productivity of 0.14 g/L/h

Plug-flow reactor 

[66]

Hfx. mediterranei

Crude glycerol

P(3HB-co-10 mol% 3HV)

Content of 76% (wt); yield of 0.19 g/g; productivity of 0.12 g/L/h

10-L bioreactor

[68]

Hfx. mediterranei

Ulva sp. hydrolysate

P(3HB-co-8 mol% 3HV)

Content of 55% (wt); productivity of 0.035 g/L/h

Duran bottle

[71]

Hfx. mediterranei

Whey sugars, sodium valerate and γ-butyrolactone

P(3HB-co-21.8 mol% 3HV-co-5.1 mo% 4HB)

Content of 87.5% (wt); yield of 0.20 g/g; productivity of 0.14 g/L/h

10-L bioreactor

[23]

Hfx. mediterranei

Crude glycerol phase and γ-butyrolactone

P(3HB-co-10.0 mol% 3HV-co-5.0 mol% 4HB)

Content of 68.5% (wt); yield of 0.16 g/g; productivity of 0.10 g/L/h

10-L bioreactor

[68]

Hgn. amylolyticum

Glucose

P(3HB-co-20.1 mol% 3HV)

Content of 26.1% (wt)

Shake flasks

[46]

Hgn. amylolyticum

Starch

P(3HB-co-18.7 mol% 3HV)

Content of 16.2% (wt)

Shake flasks

[46]

Hgn. amylolyticum

Glycerol

P(3HB-co-19.6 mol% 3HV)

Content of 7.2% (wt)

Shake flasks

[46]

Hgm. borinquense

Sugarcane bagasse hydrolysate

P(3HB-co-13.29 mol% 3HV)

Content of 45.7% (wt); yield of 0.253 g/g; productivity of 0.0113 g/L/h

Shake flasks

[43]

Nnm. ajinwuensis

Glucose

P(3HB-co-13.93 mol% 3HV)

Content of 61.02% (wt); productivity of 0.21 g/L/h

Repeated shake flasks

[45]