Fig. 1
Summary of the PHA research achievements in Haloarchaea and Halophilic bacteria. Halophiles with strong PHA-accumulation ability are mined from various hypersaline habitats. PHA production cost is closely related with substrate usage, fermentation process, and PHA recovery. Halophiles are able to utilize a wide-range of low-cost substrates. PHA recovery from halophiles can be easily done by cell lysis using tap-water. The physicochemical parameters and fermentation modes have been optimized to enhance PHA production in halophiles. With the aim of genome sequencing technology and genetic manipulation tools, various PHA related genes, enzymes and pathways have been identified. With the help of advanced metabolic engineering tools and strategies, more efficient microbial cell factory has been developed for PHA production using halophiles