Fig. 4

A Surface topology of EstM2 showing the binding of dimethyl phthalate within the catalytic pocket (pink) via electrostatic interaction with active site residues Ser68 and Trp343 based on docking analysis; B Lucid view showing hydrophobic interactions of dimethyl phthalate with different residues at the catalytic pocket of EstM2; C Alignment of other phthalate esters within the catalytic pocket of EstM2, as obtained from docking studies: diethyl phthalate (a), di-n-butyl phthalate (b), butyl benzyl phthalate (c), diphenyl phthalate (d), monomethyl phthalate (e), monoethyl phthalate (f), monobenzyl phthalate (g) and monophenyl phthalate (h)