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Table 1 Effect of the different C-terminal truncations of human FMO3 on the conversion of the test substrate, tamoxifen, compared to the full-length protein

From: Production of drug metabolites by human FMO3 in Escherichia coli

FMO3

Conversion (%)

Full-length

78.0 ± 2.0

516X

4.0 ± 0.2

505X

10.0 ± 0.4

493X

1.0 ± 0.1

  1. The experiments were carried out in triplicates. Data represent the mean (± standard deviation, SD) of the three independent experiments