Fig. 3
From: Production of drug metabolites by human FMO3 in Escherichia coli
Human FMO3-based whole-cell conversion of GSK5182, clomiphene, tozasertib and dasatinib to their corresponding N-oxide metabolites within a 24-h period. Experiments were performed in triplicates with the error bars representing the standard deviation. No metabolite was detected in the control experiments within 24 h (non-transformed E. coli JM109 cells in the presence of the four different substrates)