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Fig. 6 | Microbial Cell Factories

Fig. 6

From: Type 2 diabetes induced microbiome dysbiosis is associated with therapy resistance in pancreatic adenocarcinoma

Fig. 6

Microbial metabolome changes in chemotherapy treatment groups: Venn diagram representing changes in microbial metabolic pathways in chemotherapy treated groups (a). Combined PLS-DA analysis of C4, D4, C4′ and D4′ datasets shows distinct clustering of all four groups (b) in which only C4 and D4′ show well separated clusters, while D4 and C4′ show similar metabolic landscape within the gut microbiome. VIP analysis across the first principal component for all four groups show distinct down-regulation for D4, C4′ and D4′, compared to C4 controls (c). List of bacterial pathways that are deregulated in T2D (i.e. D4) and T2D group treated with chemotherapy or D4′ (d)

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Microbial Cell Factories

ISSN: 1475-2859

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