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Fig. 2 | Microbial Cell Factories

Fig. 2

From: Type 2 diabetes induced microbiome dysbiosis is associated with therapy resistance in pancreatic adenocarcinoma

Fig. 2

T2D mice had tumors with increased fibrosis and stem-like population: H&E section of the pancreatic tumors (a), Picrosirius red staining showing deposition of collagen in T2D mice that were unchanged upon treatment with Gem/Pac (b). T2D tumors showed increased proliferation (c) and CD133+ (d) staining that remained unchanged with therapy. In our in vitro experiments, conditions of high glucose increased expression of stemness genes in MIA-PACA2 (e) and Su86.86 (f) cell lines

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