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Fig. 3 | Microbial Cell Factories

Fig. 3

From: Biosynthetic engineering of the antifungal, anti-MRSA auroramycin

Fig. 3

Engineering glycosylation. a LCMS spectra of engineered S. roseosporus strains with 13 kb and aurS4 deletions within the BGC. b LCMS spectra of engineered S. roseosporus strains with no deletion, aurS10, aurS12 and aurS13 deletions within the BGC. c Table depicting the genes that were deleted, their annotated gene products and resulting metabolite produced by S. roseosporus strains carrying the deletion. Length refers to the number of amino acid residues of the indicated gene product. d Putative glycosylation scheme of auroramycin. AurS10 is not essential for auroramycin glycosylation but increases the efficiency of the second glycosylation reaction

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