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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Integration of a multi-step heterologous pathway in Saccharomyces cerevisiae for the production of abscisic acid

Fig. 1

Schematic of relevant metabolic pathways in S. cerevisiae and B. cinerea. The enzymatic reactions framed in yellow are present in S. cerevisiae, while the grey box represents the heterologous reactions catalysed by enzymes from B. cinerea (Pathway according to Takino et al. [18]). Genes modified or integrated in at least one of the engineered S. cerevisiae strains are shown in blue. CoA coenzyme A, HMG-CoA 3-hydroxy-3-methylglutaryl-CoA, MVA mevalonic acid, MVA-P phosphomevalonate, MVA-PP diphosphomevalonate, IPP isopentenyl diphosphate, DMAPP dimethylallyl diphosphate, GPP geranyl diphosphate, FPP farnesyl diphosphate, FOH farnesol, ABA abscisic acid, α-KG α-ketoglutarate, Glu glutamate, α-IE α-ionylideneethane, α-IAA α-ionylideneacetic acid, DH-α-IAA 1′,4′-trans-dihydroxy-α-ionylideneacetic acid

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