Metabolic engineering and transcriptomic analysis of Saccharomyces cerevisiae producing p-coumaric acid from xylose

Table 1 Examples of microbial production of aromatic amino acid derivatives (AAAD)

Product	Titer	Yield	Organism	Feedstock	Culture style	Reference
trans-Cinnamic acid	151 mg/L	0.016 g/g	E. coli	Arabinose	Batch (shake flask)	[68]
Styrene	29 mg/L	1.44 mg/g	S. lividans	Glucose	Batch (shake flask)	[69]
p-Hydroxystyrene	2.52 g/L	0.027 g/g	P. putida	Glucose	Fed-batch	[70]
p-Hydroxybenzoic acid	2.3 g/L	0.11 g/g	E. coli	Glucose, xylose	Fed-batch	[71]
p-Aminobenzoic acid	215 mg/L	N.E.	S. cerevisiae	Glycerol, ethanol	Fed-batch	[72]
p-Coumaric acid	2.4 g/L	0.013 g/g	S. cerevisiae	Glucose	Batch	[12]
Resveratrol	0.8 g/L	NE	S. cerevisiae	Glucose, ethanol	Fed-batch	[35]

ISSN: 1475-2859