Fig. 4
From: 5-Aminolevulinic acid fermentation using engineered Saccharomyces cerevisiae
ALA production by combinatorial mutant strains affecting both ALA synthesis and citrate and isocitrate metabolism with 5 mM glycine added to the cultures. a Cell concentration (g-cell/L); b intracellular ALA content (mg/g DCW); c volumetric ALA concentration (mg/L). Gray and black bars represent values after cultivation for 24 and 48 h, respectively. The values are presented as means, with error bars showing SD (n = 3). p-values are represented when they show statistically significant differences among the engineered strains by Student’s t-test (p < 0.05, analysis of variance)