Fig. 2From: Specific growth rate governs AOX1 gene expression, affecting the production kinetics of Pichia pastoris (Komagataella phaffii) PAOX1-driven recombinant producer strains with different target gene dosagePichia pastoris physiological response to an increase in CRL1 gene dosage in fed-batch (FB) cultivations. a Specific methanol consumption rate (qs), overall biomass-to-substrate yield (YX/S*). b Specific oxygen uptake rate (\(q_{{O_{2} }}\)), specific carbon dioxide production rate (\(q_{{CO_{2} }}\)) and respiratory quotient (RQ)Back to article page