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Table 1 Metabolites and biomass production by Y. lipolytica strains at the end of the shake-flask experiment (96 h) and bioreactor experiment (144 h) under oxygen limitation conditions

From: Heterologous overexpression of bacterial hemoglobin VHb improves erythritol biosynthesis by yeast Yarrowia lipolytica

Strain

Erythritol [g/l]

Arabitol [g/l]

Mannitol [g/l]

Citric acid [g/l]

Biomass [g/l]

Shake-flask experiment

 A101

10.06 ± 0.5a

1.26 ± 0.1

0.53 ± 0.05

1.33 ± 0.36

8.80 ± 1.2

 AJD pAD-VHb

18.42 ± 3.2a

1.32 ± 0.6

1.55 ± 1.6

3.43 ± 1.1

7.20 ± 0.3

Bioreactors experiment

 A101

44.20 ± 3.5b

1.60 ± 0.3

3.95 ± 0.2

17.85 ± 7.4

32.20 ± 2.5

 AJD pAD-VHb

55.75 ± 4.2b

1.75 ± 1.1

3.70 ± 2.4

23.75 ± 11.2

28.80 ± 3.5

  1. aStatistically significant at p ≤ 0.05
  2. bStatistically significant at p ≤ 0.1
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Microbial Cell Factories

ISSN: 1475-2859

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