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Table 1 LAB species with available genome-scale metabolic models

From: A metabolic reconstruction of Lactobacillus reuteri JCM 1112 and analysis of its potential as a cell factory

Species Hetero-/homo-fermenter Main applications and distinguishing characteristics Genome size (Mb) References
Lactobacillus reuteri Hetero- Produces Vitamin B12, 1,3-PDO, 3-HPA; used as probiotic and potential cell factory 2.0 [52], (This study)
Leuconostoc mesenteroides Hetero- Used in food fermentations (many non-dairy); malolactic fermentation; aroma production in foods 2.0 [29, 39]
Lactobacillus plantarum Facultatively hetero- Used in food fermentations, probiotics and potential cell factory 3.3 [61]
Lactobacillus casei Facultatively hetero- Used in food fermentations, probiotics and potential cell factory 2.9 [62]
Lactococcus lactis Homo- Used in dairy fermentations and potential cell factory 2.4 [38, 16]
Streptococcus thermophilus Homo- Used in dairy fermentations; fewer amino acid auxotrophies than other LAB, missing PPP genes 1.9 [42]