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Fig. 2 | Microbial Cell Factories

Fig. 2

From: Construction of a novel MK-4 biosynthetic pathway in Pichia pastoris through heterologous expression of HsUBIAD1

Fig. 2

Bioinformatic analysis of the aromatic prenyltransferase (aPT) HsUBIAD1. a Phylogenetic analysis of HsUBIAD1 with the Mega X program. The phylogenetic tree was divided into two distinct clades: blue, UbiA family of membrane-bound aromatic prenyltransferases; green, menA family of membrane-bound aromatic prenyltransferases; yellow, soluble aromatic prenyltransferases. b Multiple sequence alignment of HsUBIAD1. The two conserved aspartate-rich motifs characteristic of the membrane-bound aromatic prenyltransferases, Ap, Aeropyrum pernix; At, Arabidopsis thaliana; Ec, Escherichia coli; Le, Lithospermum erythrorhizon; Os, Oryza sativa; Sc, Saccharomyces cerevisiae; Bl, Bifidobacterium longum; Kp, Klebsiella pneumoniae; Pa, Papio anubis; Pt, Piliocolobus tephrosceles; Hs, Homo sapiens

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