Fig. 6
From: Improvement of Fab expression by screening combinatorial synonymous signal sequence libraries
Average expression levels of single codon variants. Each expressed single codon variant and parent Fab0 are represented on the x-axis. The average expression levels and the standard deviation from five independent expressions are represented. The average expression levels of single codon variant Leu-5 CTA was compared to Leu-5 CTG and non-optimal [Leu-4]-[Leu-5]-[Pro-6] codon run variant. The average expression levels of single codon variant L15 CTA was compared to Leu-15 CTG. In addition Non-optimal [Leu-4]-[Leu-5]-[Pro-6] codon run variant was compared to the Leu-5 CTG variant. All comparison combinations are indicated by braces and p-values of the comparisons are shown above the braces