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Fig. 6 | Microbial Cell Factories

Fig. 6

From: Optimal proteome allocation strategies for phototrophic growth in a light-limited chemostat

Fig. 6

Comparison of cellular and culture properties between the \(\text {P}_{\mathrm{E}}\)-strategy and WT-strategy. Proteome allocation was optimized for culture productivity for different dilution rates D and \(I_0=440\ \upmu \text {E m}^{-2}\ \text {s}^{-1}\), and compared to the respective values obtained for the WT-strategy. a The effective growth rate as a function of the average light intensity \(\hat{I}\). The \(\text {P}_{\mathrm{E}}\)-strategy results in a reduced effective growth rate at low effective light intensities. b The cellular light attenuation coefficient \(\alpha\). c The fraction of protein PSU (light harvesting and photosynthesis) as a fraction of cell mass. d The resulting population density \(\varrho\) as a function of the average light intensity. e The optical depth \(\theta = \alpha \cdot {\varrho }\) of both cultures. f The overall volumetric productivity of both optimization strategies as a function of the dilution rate. Despite the significant differences in proteome allocation, the differences in volumetric productivity remain small

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