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Fig. 5 | Microbial Cell Factories

Fig. 5

From: Optimal proteome allocation strategies for phototrophic growth in a light-limited chemostat

Fig. 5

Comparison of the cellular composition for different proteome allocation strategies. a \(\text {P}_{\mathrm{E}}\)-strategy: the protein allocation optimized for maximal culture productivity at a dilution rate of \(D=0.026\ \text {h}^{-1}\) with \(I_0=440\ \upmu \text {E m}^{-2}\ \text {s}^{-1}\). b WT-strategy: the protein allocation is optimized to give rise to a maximal effective growth rate for the respective average light intensity at the same dilution rate and incident light intensity. The \(\text {P}_{\mathrm{E}}\)-strategy results in a significant reduction of light-harvesting protein complexes (PSU). Instead, intracellular metabolites are accumulated. For simplicity, the cellular composition is shown without (protein and metabolic) quota components (quota components correspond to \(\approx 77.2\%\) of cellular dry weight)

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