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Table 5 Yield and consumption of NADPH in recombinant M. circinelloides strains under different nitrogen concentrations

From: 13C metabolic flux analysis on roles of malate transporter in lipid accumulation of Mucor circinelloides

Strains Condition NADPH yield NADPH consumption
PP pathway POM cycle TCA cycle Biosynthesis
G6PD 6PGD ME ICDH Lipid Protein Nucleic acid
MU522 HN 0.315 0.308 0.105 0.987 0.127 1.514 0.075
LN 0.397 0.389 0.114 0.789 0.146 1.486 0.056
MU241 HN 0.349 0.332 0.084 0.941 0.141 1.482 0.082
LN 0.401 0.388 0.107 0.732 0.213 1.361 0.056
Mc-MT-1 HN 0.366 0.352 0.097 0.857 0.135 1.473 0.066
LN 0.423 0.417 0.115 0.662 0.238 1.321 0.059
Mc-MT-2 HN 0.384 0.371 0.089 0.869 0.144 1.489 0.084
LN 0.459 0.424 0.102 0.641 0.242 1.331 0.052
  1. Data were obtained from the flux distribution presented in Fig. 5. Values are expressed in mol NADPH/mol glucose consumed
  2. G6PD glucose 6-phosphate dehydrogenase, 6PGD 6-phosphogluconate dehydrogenase, ME malic enzyme, ICDH isocitrate dehydrogenase