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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Metabolic engineering of roseoflavin-overproducing microorganisms

Fig. 1

Enzymes RibC (EC 2.7.1.26), RosB (EC 2.6.1.114), RosC (unknown) and RosA (EC 2.1.1.343) responsible for synthesis of roseoflavin (RoF) from riboflavin (RF) via the intermediates RP (riboflavin-5′-phosphate), AFP (8-demethyl-8-amino-riboflavin-5′-phosphate) and AF (8-demethyl-8-amino-riboflavin) [17, 19]. RosA is a dimethyltransferase and first generates the monomethylated form of AF, 8-demethyl-8-methylamino-riboflavin (MAF) (not shown), prior to synthesizing RoF [19]

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