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Table 2 Validated mutations in Bs-H74

From: Genetic variants of the oppA gene are involved in metabolic regulation of surfactin in Bacillus subtilis

Gene Mutation Gene function
RBAM_007770 V209A (GTA → GCA); V230L (GTA → TTA); I239V (ATA → GTA) Collagen-like protein, colony and biofilm formation
oppA W519R (TGG → CGG) Oligopeptide transport protein
rapA P259L (CCG → CTG) Transcriptional repressor of sporulation, control of sporulation initiation
araM Q226K (CAG → AAG) Glycerol-1-phosphate dehydrogenase, biosynthesis of phosphoglycerolipids
RBAM_005790 C → T intergenic (+ 390/− 228) Putative transcriptional repressor of sporulation and degradative enzymes production
czcD + 38 bp intergenic (− 6/− 187) Cation efflux, resistance against Zn, Cu, Co, Ni
ycgO I238N (ATC → AAC) High affinity proline permease, proline uptake
nasD E307D (GAA → GAC) Utilization of nitrite as nitrogen source