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Table 1 Identification of differentially regulated cellular proteins of Bacillus subtillis

From: Genetic variants of the oppA gene are involved in metabolic regulation of surfactin in Bacillus subtilis

Accession number Gene Description P value Fold change Log.Fold change
16078991 DhaS Aldehyde dehydrogenase 0.00 0.05 − 4.41
154687531 GapA Glyceraldehyde-3-phosphate dehydrogenase, ccpA indirectly regulated 0.00 0.08 − 3.62
154687186 PckA Phosphoenolpyruvate carboxykinase, ccpN repression 0.01 0.08 − 3.68
15616502 PutC 1-Pyrroline-5-carboxylate dehydrogenase, codY repression 0.00 0.10 − 3.31
16078863 CitB Aconitate hydratase, ccpA regulated 0.00 0.12 − 3.11
52082083 DegU Two-component regulator, ccpA regulated 0.01 0.09 − 3.50
34763277 RpoA RNA polymerase alpha subunit, interact with the CcpA protein [47] 0.00 0.13 − 2.97
52080062 AcoL Dihydrolipoamide dehydrogenase, ccpA regulated 0.02 0.10 − 3.39
16080734 AtpB ATP synthase 0.02 0.14 − 2.83
154685773 MtnD Acireductone dioxygenase, methionine salvage pathway 0.00 0.14 − 2.83
154684814 ProA 1-Pyrroline-5-carboxylate dehydrogenase, amino acid/nitrogen metabolism 0.00 0.14 − 2.83
154687206 PurC Naphthoate synthase, nucleotide metabolism 0.05 0.11 − 3.21
154686652 PepT Peptidase T (tripeptidase), utilization of peptides 0.00 0.19 − 2.43
37781613 SodA SOD, important for survival of ethanol and paraquat stresses and at low temperatures 0.00 0.20 − 2.31
154687051 Pyk Pyruvate kinase, glycolysis pathway 0.01 0.19 − 2.38
154687044 Mdh Malate dehydrogenase, ccpA regulated 0.01 0.18 − 2.47
154686893 CymR Pleiotropic regulator of sulfur metabolism, sulfur metabolism 0.02 0.18 − 2.48
154688140 PurA Adenylosuccinate synthetase, interact with the CcpA protein [47] 0.01 0.24 − 2.06
154684785 YceD Stress adaption protein 0.00 0.24 − 2.05
154685945 FtsZ Cell division protein, interact with the CcpA protein [47] 0.09 0.16 − 2.63
63146095 IspA Intracellular serine protease, codY repression 0.06 0.16 − 2.65
154686374 PupG Purine nucleoside phosphorylase, ccpA regulated 0.01 0.24 − 2.07
194014533 PdhB Pyruvate dehydrogenase, TCA cycle 0.00 0.26 − 1.96
154687585 ClpP ATP-dependent Clp protease proteolytic subunit 0.00 0.24 − 2.04
154685670 Ndh NADH dehydrogenase (menaquinone 7 and no proton), respiration 0.00 0.27 − 1.89
154687897 RocA 1-Pyrroline-5-carboxylate dehydrogenase, codY repression 0.05 0.22 − 2.17
16080001 Tpx Putative peroxiredoxin, spx regulated 0.00 0.25 − 2.03
154688008 PepT Peptidase T, amino acid/nitrogen metabolism 0.00 0.30 − 1.74
154687826 YwjH Putative translaldolase, pentose phosphate pathway 0.01 0.32 − 1.63
216396 GlnA Glutamine synthetase, interact with the CcpA protein [47] 0.05 0.20 − 2.35
154687185 MetK S-Adenosylmethionine synthetase, methionine salvage pathway 0.08 0.21 − 2.22
16078208 OppA Oligopeptide ABC transporter, uptake of peptides/codY repression 0.01 0.24 − 2.05
221311046 GbsR Regulation of osmoprotection 0.14 5.27 2.40
154685807 DnaK Chaperone protein 0.00 3.27 1.71
154687392 FadA Acyl-CoA acetyltransferase, fatty acid degradation 0.00 4.71 2.24
52081769 FadE Acyl-CoA dehydrogenase, fatty acid degradation 0.01 5.44 2.44
154686777 IspH Non-mevalonate pathway, biosynthesis of lipids 0.04 5.32 2.41
154688074 IolD Formation of 5-deoxy-d-glucuronic acid, ccpA regulated 0.04 5.50 2.46
154684631 TufA Elongation factor Tu 0.01 5.42 2.44
154688042 HutI Imidazolonepropionase, ccpA regulated 0.00 4.47 2.16
154688124 RocD Omithine-oxo-acid transaminase, codY repression 0.01 4.74 2.24
154685878 PdhD Dihydrolipoamide dehydrogenase, TCA cycle 0.01 6.07 2.60
154687798 AtpA ATP synthase subunit 0.04 10.98 3.46
154687827 FbaA Fructose-bisphosphate aldolase, interact with the CcpA protein [47] 0.00 9.73 3.28
1389732 MetE Methionine synthetase, methionine salvage pathway 0.12 20.94 4.39
154686979 SdhB Succinate dehydrogenase, TCA cycle 0.07 26.59 4.73
154685475 YhfE Putative endoglucanase 0.02 35.31 5.14