Table 1 Identification of differentially regulated cellular proteins of Bacillus subtillis
Accession number | Gene | Description | P value | Fold change | Log.Fold change |
|---|---|---|---|---|---|
16078991 | DhaS | Aldehyde dehydrogenase | 0.00 | 0.05 | − 4.41 |
154687531 | GapA | Glyceraldehyde-3-phosphate dehydrogenase, ccpA indirectly regulated | 0.00 | 0.08 | − 3.62 |
154687186 | PckA | Phosphoenolpyruvate carboxykinase, ccpN repression | 0.01 | 0.08 | − 3.68 |
15616502 | PutC | 1-Pyrroline-5-carboxylate dehydrogenase, codY repression | 0.00 | 0.10 | − 3.31 |
16078863 | CitB | Aconitate hydratase, ccpA regulated | 0.00 | 0.12 | − 3.11 |
52082083 | DegU | Two-component regulator, ccpA regulated | 0.01 | 0.09 | − 3.50 |
34763277 | RpoA | RNA polymerase alpha subunit, interact with the CcpA protein [47] | 0.00 | 0.13 | − 2.97 |
52080062 | AcoL | Dihydrolipoamide dehydrogenase, ccpA regulated | 0.02 | 0.10 | − 3.39 |
16080734 | AtpB | ATP synthase | 0.02 | 0.14 | − 2.83 |
154685773 | MtnD | Acireductone dioxygenase, methionine salvage pathway | 0.00 | 0.14 | − 2.83 |
154684814 | ProA | 1-Pyrroline-5-carboxylate dehydrogenase, amino acid/nitrogen metabolism | 0.00 | 0.14 | − 2.83 |
154687206 | PurC | Naphthoate synthase, nucleotide metabolism | 0.05 | 0.11 | − 3.21 |
154686652 | PepT | Peptidase T (tripeptidase), utilization of peptides | 0.00 | 0.19 | − 2.43 |
37781613 | SodA | SOD, important for survival of ethanol and paraquat stresses and at low temperatures | 0.00 | 0.20 | − 2.31 |
154687051 | Pyk | Pyruvate kinase, glycolysis pathway | 0.01 | 0.19 | − 2.38 |
154687044 | Mdh | Malate dehydrogenase, ccpA regulated | 0.01 | 0.18 | − 2.47 |
154686893 | CymR | Pleiotropic regulator of sulfur metabolism, sulfur metabolism | 0.02 | 0.18 | − 2.48 |
154688140 | PurA | Adenylosuccinate synthetase, interact with the CcpA protein [47] | 0.01 | 0.24 | − 2.06 |
154684785 | YceD | Stress adaption protein | 0.00 | 0.24 | − 2.05 |
154685945 | FtsZ | Cell division protein, interact with the CcpA protein [47] | 0.09 | 0.16 | − 2.63 |
63146095 | IspA | Intracellular serine protease, codY repression | 0.06 | 0.16 | − 2.65 |
154686374 | PupG | Purine nucleoside phosphorylase, ccpA regulated | 0.01 | 0.24 | − 2.07 |
194014533 | PdhB | Pyruvate dehydrogenase, TCA cycle | 0.00 | 0.26 | − 1.96 |
154687585 | ClpP | ATP-dependent Clp protease proteolytic subunit | 0.00 | 0.24 | − 2.04 |
154685670 | Ndh | NADH dehydrogenase (menaquinone 7 and no proton), respiration | 0.00 | 0.27 | − 1.89 |
154687897 | RocA | 1-Pyrroline-5-carboxylate dehydrogenase, codY repression | 0.05 | 0.22 | − 2.17 |
16080001 | Tpx | Putative peroxiredoxin, spx regulated | 0.00 | 0.25 | − 2.03 |
154688008 | PepT | Peptidase T, amino acid/nitrogen metabolism | 0.00 | 0.30 | − 1.74 |
154687826 | YwjH | Putative translaldolase, pentose phosphate pathway | 0.01 | 0.32 | − 1.63 |
216396 | GlnA | Glutamine synthetase, interact with the CcpA protein [47] | 0.05 | 0.20 | − 2.35 |
154687185 | MetK | S-Adenosylmethionine synthetase, methionine salvage pathway | 0.08 | 0.21 | − 2.22 |
16078208 | OppA | Oligopeptide ABC transporter, uptake of peptides/codY repression | 0.01 | 0.24 | − 2.05 |
221311046 | GbsR | Regulation of osmoprotection | 0.14 | 5.27 | 2.40 |
154685807 | DnaK | Chaperone protein | 0.00 | 3.27 | 1.71 |
154687392 | FadA | Acyl-CoA acetyltransferase, fatty acid degradation | 0.00 | 4.71 | 2.24 |
52081769 | FadE | Acyl-CoA dehydrogenase, fatty acid degradation | 0.01 | 5.44 | 2.44 |
154686777 | IspH | Non-mevalonate pathway, biosynthesis of lipids | 0.04 | 5.32 | 2.41 |
154688074 | IolD | Formation of 5-deoxy-d-glucuronic acid, ccpA regulated | 0.04 | 5.50 | 2.46 |
154684631 | TufA | Elongation factor Tu | 0.01 | 5.42 | 2.44 |
154688042 | HutI | Imidazolonepropionase, ccpA regulated | 0.00 | 4.47 | 2.16 |
154688124 | RocD | Omithine-oxo-acid transaminase, codY repression | 0.01 | 4.74 | 2.24 |
154685878 | PdhD | Dihydrolipoamide dehydrogenase, TCA cycle | 0.01 | 6.07 | 2.60 |
154687798 | AtpA | ATP synthase subunit | 0.04 | 10.98 | 3.46 |
154687827 | FbaA | Fructose-bisphosphate aldolase, interact with the CcpA protein [47] | 0.00 | 9.73 | 3.28 |
1389732 | MetE | Methionine synthetase, methionine salvage pathway | 0.12 | 20.94 | 4.39 |
154686979 | SdhB | Succinate dehydrogenase, TCA cycle | 0.07 | 26.59 | 4.73 |
154685475 | YhfE | Putative endoglucanase | 0.02 | 35.31 | 5.14 |