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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Reconstruction of metabolic pathway for isobutanol production in Escherichia coli

Fig. 1

The synthetic metabolic pathway for isobutanol production in E. coli. PEP, phosphoenolpyruvate; AcCoA, acetyl coenzyme A; Pyr, pyruvate; NADPH, reduced nicotinamide adenine dinucleotide phosphate; NADP+, oxidised NADPH; NADH, reduced nicotinamide adenine dinucleotide; NAD+, oxidised NADH; G6P, glucose 6-phosphate; F6P, fructose 6-phosphate; FBP, fructose 1,6-bisphosphate; GAP, glyceraldehyde 3-phosphate; DHAP, dihydroxyacetone phosphate; PGA, glycerate 3-phosphate; 6PGL, 6-phospho-d-glucono-1,5-lactone; 6PGc, 6-phospho-d-gluconate; 2ddg6p, 2-dehydro-3-deoxy-d-gluconate 6-phosphate; Ru5P, d-ribulose 5-phosphate; R5P, d-ribose 5-phosphate; Xu5P, d-xylulose 5-phosphate; S7P, d-sedoheptulose 7-phosphate; E4P, d-erythrose 4-phosphate; pgi, glucose-6-phosphate isomerase; gntR, DNA-binding transcriptional repressor; gnd, 6-phosphogluconate dehydrogenase; pflB, pyruvate formate lyase; ldhA, d-lactate dehydrogenase; pta, phosphate acetyltransferase; zwf, glucose-6-phosphate dehydrogenase; pgl, 6-phosphogluconolactonase; edd, phosphogluconate dehydratase; eda, KHG/KDPG aldolase; ackA, acetate kinase; alsS, acetolactate synthase; ilvC, ketol-acid reductoisomerase; ilvD, dihydroxy-acid dehydratase; kivd, 2-ketoisovalerate decarboxylase; adhA, alcohol dehydrogenase

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