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Fig. 3 | Microbial Cell Factories

Fig. 3

From: In vivo continuous evolution of metabolic pathways for chemical production

Fig. 3

Equipment maintaining continuous culture. a In-vial continuous cultivation system. Each vial has an independent control logic, enabling parallel and compartmentalised continuous cultivation in macroscale. The whole system is designed to be programmable, empowering tailor-made continuous cultivation to fulfil the needs of each laboratories. b Microfluidic-based continuous cultivation system. Due to the scale of this system, single-cell analysis has been made possible, removing the barrier set by bulk analysis. Automation without human intervention can be achieved by using programmable parts, e.g., programmable syringe pumps. c Droplet-based continuous cultivation system. Almost all the operations involved in continuous cultivation can be performed automatically in this system in compartments, thus achieving rapid enrichment and high-throughput culturing system

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