Fig. 4From: Spontaneous C-cleavage of a truncated intein as fusion tag to produce tag-free VP1 inclusion body nanoparticle vaccine against CVB3-induced viral myocarditis by the oral routeVP1 IBs cytotoxicity assay and tolerance of mice to oral VP1 IBs administration. a Cultured HeLa cell growth in absence and in presence of increasing amounts of VP1 IBs added to the culture media. b Body weight of animals during oral administration of VP1 IBs compared with control mice. c Food intake (per day and accumulated values) of mice during oral administration of VP1 IBs compared with control mice. d Histological sections of the intestine of VP1 IBs oral administered mice and control miceBack to article page