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Table 1 The zone of inhibition tests on the fermentation broths of the wild-type and different SSP_Lrp mutants

From: Engineering of leucine-responsive regulatory protein improves spiramycin and bitespiramycin biosynthesis

Strains

Characteristics

Zone of inhibition (mm)

1941

S. spiramyceticus 1941 (wild type)

19.5 ± 1.1

1941-C

1941::ermEp*-SSP_Lrp

15.2 ± 0.6

ΔSSP_Lrp-SP

Truncated SSP_Lrp at the C terminal

21.6 ± 0.5

ΔSSP_Lrp -SP–C

ΔSSP_Lrp-SP::ermEp*-SSP_Lrp

20.1 ± 0.7

ΔSSP_Lrp

Inactivation of the SSP_Lrp gene

20.8 ± 0.8