Fig. 1

The putative pathway and analysis schematic diagram of glucose repression in K. marxianus. a Putative signaling pathway of glucose repression in K. marxianus. The orange color icons indicated that the correspondent gene was disrupted and the dash icons indicated that the gene was not found in genome of K. marxianus based on theoretical translation or homology analysis; the circles indicate regulators, the squares indicate glucose sensors, while rectangles indicate enzymes. b Schematic diagram of the analysis process on glucose repression of xylose utilization in K. marxianus. HXK1: hexokinase; GLK1: glucokinase; SNF1: sucrose non-fermenting, AMP-activated S/T protein kinase; CYR1: adenylate cyclase; RAS: GTPaes; MIG1: multicopy inhibitor of GAL gene expression; ADR1: alcohol dehydrogenase ii synthesis regulator; CAT8: CATabolite repression; NRG1: negative regulator of glucose-repressed genes; MSN2: multicopy suppressor of SNF1 mutation; RDS2: regulator of drug sensitivity; RGT1: restores glucose transport