Ketone intermediate | Alcohol yield % | |||
---|---|---|---|---|
PBS | PBS with glucose | PBS with sorbitol | (S)-enantiomer | |
Talampanel ketone intermediate (compound 1) | 1.25 | 79 | 87 | 90 |
MA-20565 ketone intermediate (compound 5) | 2.75 | 37 | 91 | 100 |
Dolastatin ketone intermediate (compound 6) | 5 | 23 | 100 | 96 |