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Fig. 1 | Microbial Cell Factories

Fig. 1

From: The metabolic switch can be activated in a recombinant strain of Streptomyces lividans by a low oxygen transfer rate in shake flasks

Fig. 1

Kinetics of recombinant S. lividans producing rAPA from M. tuberculosis in conventional normal (NF, squares), coiled (CF, circles), and baffled (BF, triangles) shake flask cultures. a Biomass dry weight growth; the inset presents the growth by a logarithmic axis. b Characteristic dissolved oxygen tension (DOT) trends in NF (continuous lane), BF (dotted lane), and CF (dashed line). c Undecylprodigiosin (RED) production. d Oxygen transfer rate (OTR) trends. e Carbon transfer rate (CTR) trends. f Respiration quotient (RQ). All cultures were carried out at 30 °C, 150 rpm, and 2.5 cm orbital-shaking diameter, in 250-mL shake flasks with 50-mL filling volume. Symbols represent the median and the standard deviation of at least three independents experiments

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Microbial Cell Factories

ISSN: 1475-2859

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