TY - JOUR AU - Elbein, A. D. PY - 2003 DA - 2003// TI - New insights on trehalose: a multifunctional molecule JO - Glycobiology VL - 13 UR - https://doi.org/10.1093/glycob/cwg047 DO - 10.1093/glycob/cwg047 ID - Elbein2003 ER - TY - JOUR AU - Costa, M. S. AU - Santos, H. AU - Galinski, E. A. PY - 1998 DA - 1998// TI - An overview of the role and diversity of compatible solutes in Bacteria and Archaea JO - Adv Biochem Eng Biotechnol VL - 61 ID - Costa1998 ER - TY - JOUR AU - Santos, H. AU - Costa, M. S. PY - 2002 DA - 2002// TI - Compatible solutes of organisms that live in hot saline environments JO - Environ Microbiol VL - 4 UR - https://doi.org/10.1046/j.1462-2920.2002.00335.x DO - 10.1046/j.1462-2920.2002.00335.x ID - Santos2002 ER - TY - CHAP AU - Lamosa, P. AU - Faria, T. Q. AU - Borges, N. AU - Neves, C. AU - Santos, H. ED - Glansdorff, N. ED - Gerday, C. PY - 2007 DA - 2007// TI - The physiological role, biosynthesis, and mode of action of compatible solutes from (hyper)thermophiles BT - Physiology and biochemistry of extremophiles PB - American Society of Microbiology CY - New York ID - Lamosa2007 ER - TY - STD TI - Santos H, Ramos A, da Costa MS. Thermostabilization, osmoprotection, and protection against desiccation of enzymes, cell components, and cells by mannosylglycerate. European patent submitted at 14/03/97 with no 97670002.1 and published in 07/01/98, Bulletin 1998/02 (EP 816509 A2, A3). Applicant: IBET. Licensed to Bitop AG in 2002; 1998. ID - ref5 ER - TY - JOUR AU - Ramos, A. AU - Raven, N. D. H. AU - Sharp, R. J. AU - Bartolucci, S. AU - Rossi, M. AU - Cannio, R. PY - 1997 DA - 1997// TI - Stabilization of enzymes against thermal stress and freeze-drying by mannosylglycerate JO - Appl Environ Microbiol. VL - 63 ID - Ramos1997 ER - TY - JOUR AU - Shima, S. AU - Hérault, D. A. AU - Berkessel, A. AU - Thauer, R. K. PY - 1998 DA - 1998// TI - Activation and thermostabilization effects of cyclic 2,3-diphosphoglycerate on enzymes from the hyperthermophilic Methanopyrus kandleri JO - Arch Microbiol VL - 170 UR - https://doi.org/10.1007/s002030050669 DO - 10.1007/s002030050669 ID - Shima1998 ER - TY - JOUR AU - Lamosa, P. AU - Burke, A. AU - Peist, R. AU - Huber, R. AU - Liu, M. Y. AU - Silva, G. PY - 2000 DA - 2000// TI - Thermostabilization of proteins by diglycerol phosphate, a new compatible solute from the hyperthermophile Archaeoglobus fulgidus JO - Appl Environ Microbiol VL - 66 UR - https://doi.org/10.1128/AEM.66.5.1974-1979.2000 DO - 10.1128/AEM.66.5.1974-1979.2000 ID - Lamosa2000 ER - TY - JOUR AU - Borges, N. AU - Ramos, A. AU - Raven, N. D. H. AU - Sharp, R. J. AU - Santos, H. PY - 2002 DA - 2002// TI - Comparative study of the thermostabilizing properties of mannosylglycerate and other compatible solutes on model enzymes JO - Extremophiles VL - 6 UR - https://doi.org/10.1007/s007920100236 DO - 10.1007/s007920100236 ID - Borges2002 ER - TY - JOUR AU - Longo, C. M. AU - Wei, Y. AU - Roberts, M. F. AU - Miller, S. J. PY - 2009 DA - 2009// TI - Asymmetric syntheses of l, l- and l,d-di-myo-inositol-1,1′-phosphate and their behavior as stabilizers of enzyme activity at extreme temperatures JO - Angew Chemie Int Ed. VL - 48 UR - https://doi.org/10.1002/anie.200900480 DO - 10.1002/anie.200900480 ID - Longo2009 ER - TY - BOOK AU - Santos, H. AU - Lamosa, P. AU - Borges, N. AU - Gonçalves, L. G. AU - Pais, T. AU - Rodrigues, M. V. PY - 2011 DA - 2011// TI - Organic compatible solutes of prokaryotes that thrive in hot environments: the importance of ionic compounds for thermostabilization PB - Springer CY - Tokyo ID - Santos2011 ER - TY - JOUR AU - Jorge, C. D. AU - Borges, N. AU - Bagyan, I. AU - Bilstein, A. AU - Santos, H. PY - 2016 DA - 2016// TI - Potential applications of stress solutes from extremophiles in protein folding diseases and healthcare JO - Extremophiles VL - 20 UR - https://doi.org/10.1007/s00792-016-0828-8 DO - 10.1007/s00792-016-0828-8 ID - Jorge2016 ER - TY - JOUR AU - Faria, T. Q. AU - Mingote, A. AU - Siopa, F. AU - Ventura, R. AU - Maycock, C. AU - Santos, H. PY - 2008 DA - 2008// TI - Design of new enzyme stabilizers inspired by glycosides of hyperthermophilic microorganisms JO - Carbohydr Res VL - 343 UR - https://doi.org/10.1016/j.carres.2008.08.030 DO - 10.1016/j.carres.2008.08.030 ID - Faria2008 ER - TY - JOUR AU - Faria, C. AU - Jorge, C. D. AU - Borges, N. AU - Tenreiro, S. AU - Outeiro, T. F. AU - Santos, H. PY - 2013 DA - 2013// TI - Inhibition of formation of α-synuclein inclusions by mannosylglycerate in a yeast model of Parkinson’s disease JO - Biochim Biophys Acta VL - 1830 UR - https://doi.org/10.1016/j.bbagen.2013.04.015 DO - 10.1016/j.bbagen.2013.04.015 ID - Faria2013 ER - TY - JOUR AU - Martins, L. O. AU - Empadinhas, N. AU - Marugg, J. D. AU - Miguel, C. AU - Ferreira, C. AU - Costa, M. S. PY - 1999 DA - 1999// TI - Biosynthesis of mannosylglycerate in the thermophilic bacterium Rhodothermus marinus. Biochemical and genetic characterization of a mannosylglycerate synthase JO - J Biol Chem VL - 274 UR - https://doi.org/10.1074/jbc.274.50.35407 DO - 10.1074/jbc.274.50.35407 ID - Martins1999 ER - TY - JOUR AU - Borges, N. AU - Jorge, C. D. AU - Gonçalves, L. G. AU - Gonçalves, S. AU - Matias, P. M. AU - Santos, H. PY - 2014 DA - 2014// TI - Mannosylglycerate: structural analysis of biosynthesis and evolutionary history JO - Extremophiles VL - 18 UR - https://doi.org/10.1007/s00792-014-0661-x DO - 10.1007/s00792-014-0661-x ID - Borges2014 ER - TY - JOUR AU - Empadinhas, N. AU - Albuquerque, L. AU - Costa, J. AU - Zinder, S. H. AU - Santos, M. AU - Santos, H. PY - 2004 DA - 2004// TI - A gene from the mesophilic bacterium Dehalococcoides ethenogenes encodes a novel mannosylglycerate synthase JO - J Bacteriol VL - 186 UR - https://doi.org/10.1128/JB.186.13.4075-4084.2004 DO - 10.1128/JB.186.13.4075-4084.2004 ID - Empadinhas2004 ER - TY - JOUR AU - Asadollahi, M. A. AU - Maury, J. AU - Patil, K. R. AU - Schalk, M. AU - Clark, A. AU - Nielsen, J. PY - 2009 DA - 2009// TI - Enhancing sesquiterpene production in Saccharomyces cerevisiae through in silico driven metabolic engineering JO - Metab Eng VL - 11 UR - https://doi.org/10.1016/j.ymben.2009.07.001 DO - 10.1016/j.ymben.2009.07.001 ID - Asadollahi2009 ER - TY - JOUR AU - Zyl, W. H. AU - Lynd, L. R. AU - Haan, R. AU - McBride, J. E. PY - 2007 DA - 2007// TI - Consolidated bioprocessing for bioethanol production using Saccharomyces cerevisiae JO - Adv Biochem Eng Biotechnol VL - 108 ID - Zyl2007 ER - TY - JOUR AU - Ro, D. -. K. AU - Paradise, E. M. AU - Ouellet, M. AU - Fisher, K. J. AU - Newman, K. L. AU - Ndungu, J. M. PY - 2006 DA - 2006// TI - Production of the antimalarial drug precursor artemisinic acid in engineered yeast JO - Nature VL - 440 UR - https://doi.org/10.1038/nature04640 DO - 10.1038/nature04640 ID - Ro2006 ER - TY - JOUR AU - Otero, J. M. AU - Cimini, D. AU - Patil, K. R. AU - Poulsen, S. G. AU - Olsson, L. AU - Nielsen, J. PY - 2013 DA - 2013// TI - Industrial systems biology of Saccharomyces cerevisiae enables novel succinic acid cell factory JO - PLoS ONE VL - 8 UR - https://doi.org/10.1371/journal.pone.0054144 DO - 10.1371/journal.pone.0054144 ID - Otero2013 ER - TY - JOUR AU - Brochado, A. R. AU - Matos, C. AU - Møller, B. L. AU - Hansen, J. AU - Mortensen, U. H. AU - Patil, K. R. PY - 2010 DA - 2010// TI - Improved vanillin production in baker’s yeast through in silico design JO - Microb Cell Fact VL - 9 UR - https://doi.org/10.1186/1475-2859-9-84 DO - 10.1186/1475-2859-9-84 ID - Brochado2010 ER - TY - JOUR AU - Janik, A. AU - Sosnowska, M. AU - Kruszewska, J. AU - Krotkiewski, H. AU - Lehle, L. AU - Palamarczyk, G. PY - 2003 DA - 2003// TI - Overexpression of GDP-mannose pyrophosphorylase in Saccharomyces cerevisiae corrects defects in dolichol-linked saccharide formation and protein glycosylation JO - Biochim Biophys Acta Gen Subj. VL - 1621 UR - https://doi.org/10.1016/S0304-4165(03)00026-6 DO - 10.1016/S0304-4165(03)00026-6 ID - Janik2003 ER - TY - JOUR AU - Hashimoto, H. AU - Sakakibara, A. AU - Yamasaki, M. AU - Yoda, K. PY - 1997 DA - 1997// TI - Saccharomyces cerevisiae VIG9 encodes GDP-mannose pyrophosphorylase, which is essential for protein glycosylation JO - J Biol Chem VL - 272 UR - https://doi.org/10.1074/jbc.272.26.16308 DO - 10.1074/jbc.272.26.16308 ID - Hashimoto1997 ER - TY - JOUR AU - Partow, S. AU - Siewers, V. AU - Bjørn, S. AU - Nielsen, J. AU - Maury, J. PY - 2010 DA - 2010// TI - Characterization of different promoters for designing a new expression vector in Saccharomyces cerevisiae JO - Yeast VL - 27 UR - https://doi.org/10.1002/yea.1806 DO - 10.1002/yea.1806 ID - Partow2010 ER - TY - JOUR AU - Sonnleitner, B. AU - Käppeli, O. PY - 1986 DA - 1986// TI - Growth of Saccharomyces cerevisiae is controlled by its limited respiratory capacity: formulation and verification of a hypothesis JO - Biotechnol Bioeng VL - 28 UR - https://doi.org/10.1002/bit.260280620 DO - 10.1002/bit.260280620 ID - Sonnleitner1986 ER - TY - JOUR AU - Crabtree, H. G. PY - 1929 DA - 1929// TI - Observations on the carbohydrate metabolism of tumours JO - Biochem J. VL - 23 UR - https://doi.org/10.1042/bj0230536 DO - 10.1042/bj0230536 ID - Crabtree1929 ER - TY - JOUR AU - Postma, E. AU - Verduyn, C. AU - Scheffers, W. A. AU - Dijken, J. P. PY - 1989 DA - 1989// TI - Enzymic analysis of the crabtree effect in glucose-limited chemostat cultures of Saccharomyces cerevisiae JO - Appl Environ Microbiol VL - 55 ID - Postma1989 ER - TY - JOUR AU - Otterstedt, K. AU - Larsson, C. AU - Bill, R. M. AU - Ståhlberg, A. AU - Boles, E. AU - Hohmann, S. PY - 2004 DA - 2004// TI - Switching the mode of metabolism in the yeast Saccharomyces cerevisiae JO - EMBO Rep Eur Mol Biol Organ VL - 5 ID - Otterstedt2004 ER - TY - JOUR AU - Nevoigt, E. AU - Stahl, U. PY - 1997 DA - 1997// TI - Osmoregulation and glycerol metabolism in the yeast Saccharomyces cerevisiae JO - FEMS Microbiol Rev VL - 21 UR - https://doi.org/10.1111/j.1574-6976.1997.tb00352.x DO - 10.1111/j.1574-6976.1997.tb00352.x ID - Nevoigt1997 ER - TY - JOUR AU - Russell, J. B. PY - 1992 DA - 1992// TI - Another explanation for the toxicity of fermentation acids at low pH: anion accumulation versus uncoupling JO - J Appl Bacteriol VL - 73 UR - https://doi.org/10.1111/j.1365-2672.1992.tb04990.x DO - 10.1111/j.1365-2672.1992.tb04990.x ID - Russell1992 ER - TY - JOUR AU - Ullah, A. AU - Orij, R. AU - Brul, S. AU - Smits, G. J. PY - 2012 DA - 2012// TI - Quantitative analysis of the modes of growth inhibition by weak organic acids in Saccharomyces cerevisiae JO - Appl Environ Microbiol VL - 78 UR - https://doi.org/10.1128/AEM.02126-12 DO - 10.1128/AEM.02126-12 ID - Ullah2012 ER - TY - JOUR AU - Abbott, D. A. AU - Knijnenburg, T. A. AU - Poorter, L. M. I. AU - Reinders, M. J. T. AU - Pronk, J. T. AU - Maris, A. J. A. PY - 2007 DA - 2007// TI - Generic and specific transcriptional responses to different weak organic acids in anaerobic chemostat cultures of Saccharomyces cerevisiae JO - FEMS Yeast Res VL - 7 UR - https://doi.org/10.1111/j.1567-1364.2007.00242.x DO - 10.1111/j.1567-1364.2007.00242.x ID - Abbott2007 ER - TY - JOUR AU - Sárvári Horváth, I. AU - Franzén, C. J. AU - Taherzadeh, M. J. AU - Niklasson, C. AU - Lidén, G. PY - 2003 DA - 2003// TI - Effects of furfural on the respiratory metabolism of Saccharomyces cerevisiae in glucose-limited chemostats JO - Appl Environ Microbiol VL - 69 UR - https://doi.org/10.1128/AEM.69.7.4076-4086.2003 DO - 10.1128/AEM.69.7.4076-4086.2003 ID - Sárvári Horváth2003 ER - TY - JOUR AU - Heer, D. AU - Sauer, U. PY - 2008 DA - 2008// TI - Identification of furfural as a key toxin in lignocellulosic hydrolysates and evolution of a tolerant yeast strain JO - Microb Biotechnol VL - 1 UR - https://doi.org/10.1111/j.1751-7915.2008.00050.x DO - 10.1111/j.1751-7915.2008.00050.x ID - Heer2008 ER - TY - JOUR AU - Guo, Z. AU - Olsson, L. PY - 2014 DA - 2014// TI - Physiological response of Saccharomyces cerevisiae to weak acids present in lignocellulosic hydrolysate JO - FEMS Yeast Res VL - 14 UR - https://doi.org/10.1111/1567-1364.12221 DO - 10.1111/1567-1364.12221 ID - Guo2014 ER - TY - JOUR AU - Hoek, P. AU - Dijken, J. P. AU - Pronk, J. T. PY - 1998 DA - 1998// TI - Effect of specific growth rate on fermentative capacity of baker’s yeast JO - Appl Environ Microbiol VL - 64 ID - Hoek1998 ER - TY - BOOK AU - Nielsen, J. AU - Villadsen, J. AU - Lidén, G. PY - 2003 DA - 2003// TI - Bioreaction engineering principles PB - Springer CY - Boston UR - https://doi.org/10.1007/978-1-4615-0767-3 DO - 10.1007/978-1-4615-0767-3 ID - Nielsen2003 ER - TY - JOUR AU - Stanley, D. AU - Bandara, A. AU - Fraser, S. AU - Chambers, P. J. AU - Stanley, G. A. PY - 2010 DA - 2010// TI - The ethanol stress response and ethanol tolerance of Saccharomyces cerevisiae JO - J Appl Microbiol VL - 109 ID - Stanley2010 ER - TY - JOUR AU - Vos, T. AU - Torre, C. o. r. t. é. s. P. AU - Gulik, W. M. AU - Pronk, J. T. AU - Daran-Lapujade, P. PY - 2015 DA - 2015// TI - Growth-rate dependency of de novo resveratrol production in chemostat cultures of an engineered Saccharomyces cerevisiae strain JO - Microb Cell Fact VL - 14 UR - https://doi.org/10.1186/s12934-015-0321-6 DO - 10.1186/s12934-015-0321-6 ID - Vos2015 ER - TY - JOUR AU - Johansson, N. AU - Quehl, P. AU - Norbeck, J. AU - Larsson, C. PY - 2013 DA - 2013// TI - Identification of factors for improved ethylene production via the ethylene forming enzyme in chemostat cultures of Saccharomyces cerevisiae JO - Microb Cell Fact VL - 12 UR - https://doi.org/10.1186/1475-2859-12-89 DO - 10.1186/1475-2859-12-89 ID - Johansson2013 ER - TY - JOUR AU - Zhang, N. AU - Gardner, D. C. AU - Oliver, S. G. AU - Stateva, L. I. PY - 1999 DA - 1999// TI - Down-regulation of the expression of PKC1 and SRB1/PSA1/VIG9, two genes involved in cell wall integrity in Saccharomyces cerevisiae, causes flocculation JO - Microbiology VL - 145 UR - https://doi.org/10.1099/13500872-145-2-309 DO - 10.1099/13500872-145-2-309 ID - Zhang1999 ER - TY - JOUR AU - Nookaew, I. AU - Papini, M. AU - Pornputtapong, N. AU - Scalcinati, G. AU - Fagerberg, L. AU - Uhlén, M. PY - 2012 DA - 2012// TI - A comprehensive comparison of RNA-Seq-based transcriptome analysis from reads to differential gene expression and cross-comparison with microarrays: a case study in Saccharomyces cerevisiae JO - Nucleic Acids Res VL - 40 UR - https://doi.org/10.1093/nar/gks804 DO - 10.1093/nar/gks804 ID - Nookaew2012 ER - TY - JOUR AU - Lõoke, M. AU - Kristjuhan, K. AU - Kristjuhan, A. PY - 2011 DA - 2011// TI - Extraction of genomic DNA from yeasts for PCR-based applications JO - Biotechniques VL - 50 UR - https://doi.org/10.2144/000113672 DO - 10.2144/000113672 ID - Lõoke2011 ER - TY - JOUR AU - Gietz, R. D. AU - Woods, R. A. PY - 2002 DA - 2002// TI - Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method JO - Methods Enzymol VL - 350 UR - https://doi.org/10.1016/S0076-6879(02)50957-5 DO - 10.1016/S0076-6879(02)50957-5 ID - Gietz2002 ER - TY - JOUR AU - Dower, W. J. AU - Miller, J. F. AU - Ragsdale, C. W. PY - 1988 DA - 1988// TI - High efficiency transformation of E. coli by high voltage electroporation JO - Nucleic Acids Res VL - 16 UR - https://doi.org/10.1093/nar/16.13.6127 DO - 10.1093/nar/16.13.6127 ID - Dower1988 ER - TY - JOUR AU - Entian, K. -. D. AU - Kötter, P. PY - 2007 DA - 2007// TI - 25 yeast genetic strain and plasmid collections JO - Methods Microbiol VL - 36 UR - https://doi.org/10.1016/S0580-9517(06)36025-4 DO - 10.1016/S0580-9517(06)36025-4 ID - Entian2007 ER - TY - BOOK AU - Guthrie, C. AU - Fink, G. R. PY - 1991 DA - 1991// TI - Guide to yeast genetics and molecular biology PB - Academic Press CY - San Diego ID - Guthrie1991 ER - TY - JOUR AU - Santos, H. AU - Lamosa, P. AU - Borges, N. PY - 2006 DA - 2006// TI - Characterization and quantification of compatible solutes in (hyper)thermophilic microorganisms JO - Methods Microbiol. VL - 35 UR - https://doi.org/10.1016/S0580-9517(08)70011-4 DO - 10.1016/S0580-9517(08)70011-4 ID - Santos2006 ER - TY - JOUR AU - Bradford, M. M. PY - 1976 DA - 1976// TI - A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding JO - Anal Biochem VL - 72 UR - https://doi.org/10.1016/0003-2697(76)90527-3 DO - 10.1016/0003-2697(76)90527-3 ID - Bradford1976 ER - TY - BOOK AU - Bergmeyer, H. U. AU - Gawehn, K. PY - 1974 DA - 1974// TI - Methods of enzymatic analysis PB - Academic Press CY - New York ID - Bergmeyer1974 ER -