Fig. 3

GABA catabolism and production of polyhydroxybutyrates (PHBs) in S. cerevisiae. The figure was adapted from Fig. 1 [87]. PHBs production starts with the reduction of succinate semialdehyde by γ-hydroxybutyric acid dehydrogenase to produce γ-hydroxybutyric acid. γ-hydroxybutyric acid and 3-hydroxybutyrate are polymerized by poly(3-hydroxybutyrate-co-4-hydroxybutyrate) synthase. 3HB formation from acetyl-CoA involves acetoacetyl-CoA thiolase and 3HB-CoA dehydrogenase. GDH1 glutamate dehydrogenase 1, GDH2 glutamate dehydrogenase 2, GDH3 glutamate dehydrogenase 3, GAD1 glutamate decarboxylase, UGA2 succinate semialdehyde dehydrogenase, GHB γ-hydroxybutyric acid, 3HB 3-hydroxybutyrate, P(3HB-co-4HB) poly(3-hydroxybutyrate-co-4-hydroxybutyrate)