E. coli HMS174(DE3) is a sustainable alternative to BL21(DE3)

Table 1 Comparison of the productivity of FHT in BL21(DE3) and HMS174(DE3)

	q_s (g/g/h)	µ (h⁻¹)	Specific titer (mg_P/g_X)
HMS174(DE3)	q_s,lac,max = 0.23 ± 0.034	0.07 ± 0.015	27 ± 0.9
BL21(DE3)	q_s,glu = 0.28 ± 0.046	0.07 ± 0.015	25 ± 0.6

A standard BL21(DE3) cultivation on glucose, induced at 0.5 mM IPTG is compared to a HMS174(DE3) cultivation induced and fed with lactose. Standard deviations were evaluated from triple measurements and calculated by error propagation

ISSN: 1475-2859