Fig. 4

Transformation of pSH71 derived plasmids induces significant genome remodeling in LR 6475 prophages. Chromosome representation of a L. reuteri JCM112 (F275) and b LJO3, representing identical genomic sequences (light gray), inverted (dark gray) and deleted (green) regions. The prophages present in LR 6475 genome are represent in yellow (phage 1) and cyan (phage 2). Arrows indicate the sense of the strand. c Transformation efficiency of LR 6475, LJO3 and LR 6475 double phage mutant (∆Φ1∆Φ2) for pJP067. Data represents the averages of three independent experiments and error bars represent standard deviation, (*p < 0.05)