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Table 1 Turnover number (kcat) for enzymes with published kinetic data used in the artemisinic acid pathway in S. cerevisiae [8]

From: An estimate is worth about a thousand experiments: using order-of-magnitude estimates to identify cellular engineering targets

Enzyme

kcat (s−1)

Reference

ERG10

NR

 

ERG13

NR

 

tHMG1

0.4a

[9]

ERG12

16

[10]

ERG8

40a

[11]

MVD1

5

[12]

IDI1

7a

[13]

ERG20

NR

 

ADS

0.2

[6]

CYP71AV1/CPR1/CYB5

NR

 

ADH1

41

[5]

ALDH1

1.5

[14]

  1. NR not reported
  2. aEstimated from specific activity