Table 1 Deduced functions of the open reading frames in the tub gene cluster
Protein | aa | Proposed function | Homolog, Origin | Identity, similarity (%) | Accession no. |
|---|---|---|---|---|---|
Orf-1 | 58 | (2Fe-2S)-binding protein | AWI43_15300, Streptomyces sp. WAC04657 | 78, 83 | KYG55615.1 |
TubA | 125 | CPH4 synthase | ToyB, Streptomyces rimosus ATCC 14673 | 65, 79 | ACF06634.1 |
TubB | 139 | Radical SAM family protein | SPAR_33961, Streptomyces sparsogenes DSM 40356 | 71, 79 | OMI34937.1 |
TubC | 199 | GTP cyclohydrolase I (GCH I) | ToyD, Streptomyces rimosus ATCC 14673 | 64, 75 | ACF06635.1 |
TubD | 385 | GMP reductase | ToyE, Streptomyces rimosus ATCC 14673 | 61, 75 | ACF06636.1 |
TubE | 194 | Phosphoribosylpyrophosphate transferase | ToyH, Streptomyces rimosus ATCC 14673 | 39, 53 | ACF06639.1 |
TubF | 422 | UbiD family decarboxylase | ASE41_09730, Streptomyces sp. Root264 | 90, 93 | KRD23282.1 |
TubG | 168 | Nudix hydrolase | ASE41_09725, Streptomyces sp. Root264 | 96, 96 | KRD23281.1 |
TubH | 314 | Carbohydrate kinase family protein | ASE41_09720, Streptomyces sp. Root264 | 82, 86 | KRD23280.1 |
TubI | 374 | MFS transporter | ASE41_09715, Streptomyces sp. Root264 | 83, 88 | KRD23279.1 |
Orf1 | 68 | Hypothetical protein | ASE41_09630, Streptomyces sp. Root264 | 41, 60 | KRD23264.1 |