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Table 1 Growth performance and intracellular Kar2/Bip level of P. pastoris X-33 carrying the aox1 promoter-controlled IP gene during batch growth in a 2 L bioreactor with different initial glycerol concentrations

From: Fate of the UPR marker protein Kar2/Bip and autophagic processes in fed-batch cultures of secretory insulin precursor producing Pichia pastoris

Glycerol (g/L) 30 60 95 125
µmax (1/h) 0.26 0.19 0.18 0.18
Osmolarity (Osmol/kg) 0.8 1.4 1.9 2.5
Relative Kar2/Bip abundance 114 123 100 116