C. glutamicum strains | CS (%)a | DCW (g L−1) | l-Lys yield (g L−1) | μ bmax (h−1) | q cLys, max. (g g−1 h−1) | α (%)d | ||
---|---|---|---|---|---|---|---|---|
24Â h | 48Â h | 24Â h | 48Â h | |||||
JL-68 | 100 | 11.48 ± 1.76 | 11.35 ± 1.52 | 10.60 ± 1.06 | 17.63 ± 0.61 | 0.21 | 0.34 ± 0.05 | 44.08 |
JL-68∆gltA | 2.60 | 0.63 ± 0.00 | 0.96 ± 0.15 | – | – | nd | nd | nd |
JL-68∆ramA | 11.46 | 6.03 ± 1.18 | 6.82 ± 2.05 | 8.01 ± 1.53 | 19.17 ± 3.45 | 0.15 | 0.53 ± 0.12 | 47.93 |
JL-68∆P1gltA (or JL-69) | 16.15 | 9.67 ± 2.13 | 9.75 ± 1.35 | 9.54 ± 2.14 | 21.44 ± 1.93 | 0.20 | 0.49 ± 0.08 | 53.60 |
JL-68∆P12gltA | 2.60 | 0.67 ± 0.05 | 1.01 ± 0.13 | – | – | nd | nd | nd |
JL-68PdapA-L1 gltA | 6.77 | 2.23 ± 0.36 | 4.92 ± 0.81 | 5.01 ± 1.15 | 14.75 ± 2.16 | 0.11 | 0.41 ± 0.17 | 36.88 |
JL-68∆prpC1 | 98.44 | 11.24 ± 1.02 | 11.53 ± 1.17 | 10.58 ± 1.37 | 17.79 ± 1.23 | 0.22 | 0.38 ± 0.11 | 44.48 |
JL-68 ∆prpC2 | 99.48 | 11.29 ± 1.31 | 11.51 ± 1.13 | 10.56 ± 1.04 | 17.73 ± 1.05 | 0.22 | 0.37 ± 0.07 | 44.33 |
JL-68∆prpC1∆prpC2 | 97.92 | 11.25 ± 1.25 | 11.50 ± 0.87 | 10.57 ± 1.12 | 17.71 ± 1.12 | 0.22 | 0.37 ± 0.06 | 44.28 |
JL-68∆gltA∆prpC1 | nd | 0.14 ± 0.01 | 0.12 ± 0.02 | – | – | nd | nd | nd |
JL-68∆gltA∆prpC2 | nd | 0.15 ± 0.01 | 0.16 ± 0.01 | – | – | nd | nd | nd |
JL-68∆gltA∆prpC1∆prpC2 | nd | 0.13 ± 0.00 | 0.13 ± 0.01 | – | – | nd | nd | nd |
JL-68∆gltA∆prpC1prpRG977A | 10.94 | 5.17 ± 1.01 | 6.03 ± 1.12 | 7.31 ± 1.15 | 20.18 ± 3.61 | 0.14 | 0.58 ± 0.33 | 50.45 |