Table 1 Proposed functions of proteins encoded by the rdm biosynthetic gene cluster in S. youssoufiensis OUC6819
Protein | Size (aa) | Proposed function | Homologs | |
|---|---|---|---|---|
Protein/organism | Accession no. (identity/similarity %) | |||
Orf(−3) | 213 | TetR/AcrR family transcriptional regulator | IF52_RS0105620/Streptomyces ruber | WP_030357119.1 (66/74) |
Orf(−2) | 418 | FAD-binding monooxygenase | BCAV_RS14010/Beutenbergia cavernae | WP_015883264.1 (59/69) |
Orf(−1) | 267 | Methyltransferase | H299_RS35255/Streptomyces sp. CNH287 | WP_051262671.1 (68/80) |
RdmA | 286 | XRE family transcriptional regulator | ASD26_RS06115/Streptomyces sp. Root1319 | WP_056788122.1 (57/65) |
RdmB | 256 | Methyltransferase | AB852_RS08905/Streptomyces uncialis | WP_073785832.1 (63/73) |
RdmC | 218 | LuxR family two-component system response regulator | KasW/Streptomyces kasugaensis | BAF79686.1 (84/91) |
RdmD | 111 | Two-component system sensor kinase | KasX/S. kasugaensis | BAF79687.1 (66/81, the 475th–585th aa) |
RdmE | 410 | Two-component system sensor kinase | KasX/S. kasugaensis | BAF79687.1 (68/75, the 31st–413rd aa) |
RdmF | 233 | PAS-LuxR regulator | AOM46_RS26735/Streptomyces sp. NBRC 109706 | WP_062215992.1 (83/89) |
RdmG | 4996 | Type I polyketide synthase | AOM46_RS26740/Streptomyces sp. NBRC 109706 | WP_078857234.1 (70/78) |
RdmH | 6440 | Type I polyketide synthase | AOM46_RS26745/Streptomyces sp. NBRC 109706 | WP_078857210.1 (71/80) |
RdmI | 9533 | Type I polyketide synthase | SHXM_01039/Streptomyces hygroscopicus XM201 | AQW47576.1 (52/63) |
RdmJ | 7252 | Type I polyketide synthase | AOM46_RS26755/Streptomyces sp. NBRC 109706 | WP_062216000.1 (74/82) |
RdmK | 498 | MFS transporter | AOK24_RS06280/Streptomyces niveiscabiei | WP_055719056.1 (76/83) |
RdmL | 398 | Ferritin | AOK24_RS06275/S. niveiscabiei | WP_055719055.1 (84/91) |
RdmM | 172 | PaaI family thioesterase | AOK24_RS06270/S. niveiscabiei | WP_055719054.1 (75/85) |
RdmN | 82 | Acyl carrier protein | AOK24_RS06265/S. niveiscabiei | WP_055719053.1 (54/75) |
RdmO | 576 | Acyl-CoA synthetase | AOK24_RS06260/S. niveiscabiei | WP_055719052.1 (66/76) |
Orf1 | 176 | Hypothetical protein | AMJ94_18775/Deltaproteobacteria bacterium SM23_61 AOK24_RS06255/S. niveiscabiei AOK24_RS06250/S. niveiscabiei | KPK85730.1 (32/53) WP055719051.1 (78/84, the 1st–79th aa) WP055719050.1 (82/89, the 81st–174th aa) |
Orf2 | 207 | DNA-binding response regulator | AOK24_RS06245/S. niveiscabiei | WP_063799404.1 (61/74) |
Orf3 | 361 | Hypothetical protein | AOK24_RS06240/S. niveiscabiei | WP_079056694.1 (56/67) |