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Fig. 4 | Microbial Cell Factories

Fig. 4

From: Characterization of the biosynthetic gene cluster of the polyene macrolide antibiotic reedsmycins from a marine-derived Streptomyces strain

Fig. 4

Phylogenetic analysis of RdmGHIJ AT domains with selected characterized ATs from type I PKSs. The percentage of replicate trees in which the associated taxa clustered together in the bootstrap test (1000 replicates) is shown next to the branches. The sequences subjected to alignment are from amphotericin gene cluster in Streptomyces nodosus, tautomycin gene cluster in Streptomyces spiroverticillatus, epothilone gene cluster in Sorangium cellulosum, and erythromycin gene cluster in Saccharopolyspora erythraea. Cluster names, producer strains and accession numbers for each of the AT domains are given in parentheses. The scale bar represents 0.1 amino acid substitution per position

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