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Fig. 2 | Microbial Cell Factories

Fig. 2

From: 13C-metabolic flux analysis of ethanol-assimilating Saccharomyces cerevisiae for S-adenosyl-l-methionine production

Fig. 2

Metabolic flux distributions (mmol/gCDW/h) for S. cerevisiae grown on glucose (a) [4] and ethanol (b) at a dilution rate of 0.06 h−1. Flux values in the central carbon metabolism are shown with 90% confidence intervals. The width of each arrow indicates best-fit value (Additional file 1: Table S11). The anabolic reactions from metabolic intermediates to biomass are represented by small arrows. The product synthesis reactions are represented by dotted arrows. These flux values are shown in Additional file 1: Table S8. G6P glucose-6-phosphate, F6P fructose-6-phosphate, DHAP dihydroxyacetone phosphate, GAP 3-phosphoglyceraldehyde, PGA 3-phosphoglycerate, PEP phosphoenolpyruvate, Pyr_c cytosolic pyruvate, Pyr_m mitochondrial pyruvate, AcCOA_c cytosolic acetyl-CoA, AcCOA_m mitochondrial acetyl-CoA, AcAl acetaldehyde, Ac acetate, IsoCit isocitrate, aKG α-ketoglutarate, Suc succinate, Mal malate, Oxa_c cytosolic oxaloacetate, Oxa_m mitochondrial oxaloacetate, 6PG 6-phosphogluconate, Ru5P ribulose-5-phosphate, R5P ribose-5-phosphate, Xu5P xylulose-5-phosphate, S7P sedoheptulose-7-phosphate, E4P erythrose-4-phosphate, Glxy glyoxylate

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