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Table 3 Selected mutants from KEIO collection [16] for improvement of DHA production by expression of pDHA4 plasmid

From: fabH deletion increases DHA production in Escherichia coli expressing Pfa genes

Gene name

Gene code

Protein

Process

fabF

b1095

Ketoacyl synthase II

Fatty acid biosynthesis

fabH

b1091

Ketoacyl synthase III

fabR

b3963

Fatty acid synthesis repressor

tesA

b0494

Acyl-CoA thioesterase I

fadE

b0221

Acyl-CoA dehydrogenase

Fatty acid degradation

fadR

b1187

Global lipid metabolism regulator

glpR

b3423

Glycerol-3-phosphate transcriptional repressor

Carbon metabolism regulation

gntR

b3438

Entner-Doudoroff pathway transcriptional repressor

phoB

b0399

Response factor. Phosphate dual regulation factor

General cell regulation

phoP

b1130

Response factor. Phosphate dual regulation factor

rpoS

b2741

Sigma factor. Represses of fadA, fadB, fadE and fadH

  1. Gene code is taken from E. coli MG1655 strain in Ecocyc database