Fig. 1
From: Corynebacterium glutamicum as platform for the production of hydroxybenzoic acids
Schematic representation of the shikimate pathway in C. glutamicum and additionally introduced enzymatic steps for hydroxybenzoate production. AroF*, AroH: 3-deoxy-d-arabinoheptulosonate-7-phosphate synthase, DAHP: 3-deoxy-d-arabinoheptulosonate-7-phosphate, Hyg5: chorismatase (3-hydroxybenzoate synthase), EPSP: 5-enolpyruvyl-shikimate-3-phosphate, Irp9: isochorismate synthase/isochorismate pyruvate lyase (salicylate synthase), PEP: phosphoenolpyruvate, QsuB: 3-dehydroshikimate dehydratase, UbiC: chorismate pyruvate lyase (4-hydroxybenzoate synthase). Irp9, Hyg5 and UbiC lead to the formation of pyruvate as a second product, which is not depicted