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Table 3 Products’ accumulation during transformation in Isaria farinosa KCh KW1.1 culture

From: Biotransformation of steroids by entomopathogenic strains of Isaria farinosa

Substrate Compounds found in the reaction mixture (%) Biotransformation time (days)
1 3 7
Adrenosterone ADR 9 ± 2.6
6β-OH-ADR 46 ± 2.8 52 ± 2.2 49 ± 3.6
Progesterone P
6β,11α-OH-P 74 ± 1.3 71 ± 2.4 64 ± 3.1
6β-OH,11-oxo-P 4 ± 0.7 5 ± 1.1 3 ± 0.9
1,4,6-triene-T 1,4,6-triene-T 5 ± 1.3
15α-OH-6,7β-epoxy-1-ene-T 37 ± 2.2 35 ± 1.4 32 ± 1.8
14α-OH-6,7β-epoxy-1-ene-T 20 ± 0.3 19 ± 0.2 16 ± 1.3
15α-OH-6,7β-epoxy-T 10 ± 0.8 13 ± 2.0 17 ± 2.4
  1. Biotransformation conditions: 100 mL of cultivation medium (3% glucose, 1% bacteriological peptone) in 300 mL Erlenmeyer flasks, 24 °C, 150 r/min for 7 day
  2. Data are the average of three independent experiments. Standard errors were indicated