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Fig. 1 | Microbial Cell Factories

Fig. 1

From: Enhancement of the catalytic activity of Isopentenyl diphosphate isomerase (IDI) from Saccharomyces cerevisiae through random and site-directed mutagenesis

Fig. 1

The MEP and MVA pathways. In the MVA pathway, a series of enzymes catalyze two molecules of acetyl-CoA into IPP, which is then isomerized by IDI to its isomer—DMAPP. In the MEP pathway, glyceraldehyde 3-phosphate and pyruvate are converted to IPP and DMAPP. At the same time, IDI as an isomerase, functions to balance the amount of IPP and DMAPP. Under the catalysis by the downstream enzymes, DMAPP enters the synthesis pathway of the target product

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